The MX beamlines BL14.1-3 at BESSY II


  • Martin Gerlach Helmholtz-Zentrum Berlin für Materialien und Energie
  • Uwe Mueller Helmholtz-Zentrum Berlin für Materialien und Energie
  • Manfred S. Weiss Helmholtz-Zentrum Berlin für Materialien und Energie



The Macromolecular Crystallography (MX) group at the Helmholtz-Zentrum Berlin (HZB) is operating three state-of-the-art synchrotron beamlines for MX at BESSY II in Berlin (Heinemann et al., 2003; Mueller et al., 2012, 2015). The radiation source for all three beamlines BL14.1-3 is a superconducting 7T-wavelength shifter. Currently, the three beam lines are the most productive stations for MX in Germany, with about 250 PDB depositions per year and over 1500 PDB depositions in total (Status 10/2015). BL14.1 and BL14.2 are energy tuneable in the range 5.5-15.5 keV, while beam line BL14.3 is a fixed-energy side station operated at 13.8 keV. The HZB-MX beamlines are in regular user operation providing close to 200 beam days per year and about 600 user shifts to approximately 100 research groups across Europe. Additional user facilities include office space adjacent to the beam lines, a sample preparation laboratory, a biology laboratory (safety level 1) and high-end computing resources.


Bowler, M. W., Uwe Mueller, U., Weiss, M. S., Sanchez-Weatherby, J., Sorensen, T., Thunnissen, M. M. G. M., . . . Cipriani, F. (2015). Automation and experience of controlled crystal dehydration: Results from the european synchrotron hc1 collaboration. Crystal Growth & Design, 15(3), 1043-1054.

Heinemann, U., Bülow, K., Mueller, U., & Umbach, P. (2003). Facilities and methods for the highthroughput crystal structural analysis of human proteins. Accounts of Chemical Research, 36(3), 157–163.

Mueller, U., Darowski, N., Fuchs, M. R., Förster, R., Hellmig, M., Paithankar, K. S., . . . Weiss, M. S. (2012). Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin. Journal of Synchrotron Radiation, 19(3), 442–449.

Mueller, U., Förster, R., Hellmig, M., Huschmann, F. U., Kastner, A., Malecki, ., . . . Weiss, M. S. (2015). The macromolecular crystallography beamlines at bessy ii of the helmholtz-zentrum berlin: Current status and perspectives. The European Physical Journal Plus, 130(7).

Cite article as: Helmholtz-Zentrum Berlin für Materialien und Energie. (2016). The MX beamlines BL14.1-3 at BESSY II. Journal of large-scale research facilities, 2, A47.